How Menopause Affects Your Skin Microbiome

skin microbiome in menopause

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Written by Lucy Sanderson, Human Nutrition Graduate, Edited by Laura Clark

Menopause brings a wave of changes to your body, and your skin is no exception. While we often hear about hormonal shifts affecting bone density or metabolism, the skin microbiome – your skin’s natural community of bacteria and microorganisms – also undergoes a significant transformation. These changes can lead to dryness, increased sensitivity, and even a higher risk of skin infections.

Why oestrogen matters for skin health

Oestrogen plays a crucial role in maintaining a balanced skin microbiome. It supports the growth of beneficial bacteria like Staphylococcus epidermidis, which acts as a natural defence against harmful pathogens. As oestrogen levels decline during menopause, the diversity and balance of these protective microbes shifts, increasing the risk of skin irritation, infections, and a weakened skin barrier.

The link between oestrogen, hydration, and skin barrier function

Beyond microbial balance, oestrogen is essential for keeping your skin hydrated and resilient. It promotes collagen production and oil (sebum) secretion — two key factors in maintaining smooth, supple skin. When oestrogen levels drop, sebum production decreases, which can lead to dryness, flakiness, and heightened sensitivity. A weakened skin barrier, combined with a disrupted microbiome, can make menopausal skin more prone to irritation and conditions like eczema.

How to support your skin microbiome during menopause

The good news? There are practical steps you can take to help maintain healthy, resilient skin during this transition:

Hydrate and moisturise

Use hydrating serums and creams containing hyaluronic acid to help replenish moisture and support a healthy skin barrier.

moisturise during menopause

Explore topical probiotics and prebiotics

Emerging evidence suggests these may help restore microbial balance and strengthen the skin barrier – a promising area of skincare research worth keeping an eye on.

Choose gentle skincare products

Avoid harsh cleansers and opt for mild, pH-balanced formulas that help protect your skin’s natural defences and support a balanced microbiome.

Support collagen production

Ingredients like retinol (if well-tolerated) and vitamin C have good evidence for supporting collagen synthesis. Topical peptides may also help – the evidence is still developing, but some signal peptides have shown promising results in stimulating skin cell activity.

eat fruit during menopause

While menopause brings inevitable changes, understanding how it affects your skin microbiome allows you to take proactive steps to maintain healthy, resilient skin. With the right skincare and lifestyle choices, you can help keep your skin feeling strong, hydrated, and balanced.

References

Pramanik, P. (2025) ‘Hormonal shifts in menopause redefine women’s microbiome and risks’, News Medical, 15 January. (Accessed: 28 January 2025).

Shah, M. G. and Maibach, H. I. (2001) ‘Estrogen and skin: an overview’, American Journal of Clinical Dermatology, 2(3), pp. 143–150.

Thornton, M. J. (2013) ‘Estrogens and aging skin’, Dermato-endocrinology, 5(2), pp. 264–270.

Zheng, Y. et al. (2022) ‘Commensal Staphylococcus epidermidis contributes to skin barrier homeostasis by generating protective ceramides’, Cell Host & Microbe, 30(3), pp. 301–313.

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